RNA Details
Disease Name
diabetic nephropathy
Tissue
kidney
RNA Symbol
mir-23b
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
NA
Target
GSBP2
Pathway
MAPK SIGNALING PATHWAY
PubMed ID
Title
MicroRNA-23b Targets Ras GTPase-Activating Protein SH3 Domain-Binding Protein 2 to Alleviate Fibrosis and Albuminuria in Diabetic Nephropathy
Year
2016
Function
Hyperglycemia regulates pathogenic processes in diabetic nephropathies through an miR-23b/G3bp2 feedback circuit involving p38 MAPK and p53.